Exemestanum [Inn-Latin]

• Antineoplastic Agents
• ATC:L02BG06

• Aromasin
• Exemestance
• Exemestane [Inn]
• Exemestane [Usan:Inn:Ban]
• Exemestano [Inn-Spanish]
• Exemestanum [Inn-Latin]

No information avaliable

C₂₀H₂₄O₂

http://www.rxlist.com/cgi/generic3/exemest.htm

Exemestanum_[Inn-Latin] FDA

Pfizer Canada Inc, numero di brevetto: 1277656

296.403 g/mol

155.13^oC

Non solubili

Solid

4.222

Compressa

Per il trattamento del carcinoma mammario avanzato nelle donne in post-menopausa la cui malattia è progredita dopo terapia con tamoxifene.

Aromatasi è un enzima che converte gli ormoni in estrogeni nelle ghiandole surrenali del corpo. Gli inibitori dell'aromatasi (AI) sono farmaci che riducono i livelli di estrogeni bloccando l'azione dell'aromatasi nel surrene ghiandole. L'AIS selettivo (ISC) selettivamente ridurre i livelli di estrogeni senza interferire con i livelli di altri ormoni steroidei che sono prodotte dalla ghiandola surrenale. Farmaci di questa classe includono anastrozolo (Arimidex ™), Letrozolo (Femara ™) ed Exemestane (Aromasin ™).

42%

Convulsioni

PATIENT INFORMATION

If clinically advisable, patients receiving OxyContin� (oxycodone hydrochloride controlled-release) tablets or
their caregivers should be given the following information by the physician, nurse, pharmacist, or caregiver:

1. Patients should be aware that OxyContin� tablets contain oxycodone, which is a morphine-like substance.

2. Patients should be advised that OxyContin� tablets were designed to work properly only if swallowed whole.
OxyContin� tablets will release all their contents at once if broken, chewed, or crushed, resulting in a risk of
fatal overdose.

3. Patients should be advised to report episodes of breakthrough pain and adverse experiences occurring during
therapy. Individualization of dosage is essential to make optimal use of this medication.

4. Patients should be advised not to adjust the dose of OxyContin� without consulting the prescribing professional.

5. Patients should be advised that OxyContin� may impair mental and/or physical ability required for the performance
of potentially hazardous tasks (e.g., driving, operating heavy machinery).

6. Patients should not combine OxyContin� with alcohol or other central nervous system depressants (sleep aids,
tranquilizers) except by the orders of the prescribing physician, because dangerous additive effects may occur,
resulting in serious injury or death.

7. Women of childbearing potential who become, or are planning to become, pregnant should be advised to consult their
physician regarding the effects of analgesics and other drug use during pregnancy on themselves and their unborn child.

8. Patients should be advised that OxyContin� is a potential drug of abuse. They should protect it from theft, and it
should never be given to anyone other than the individual for whom it was prescribed.

9. Patients should be advised that they may pass empty matrix "ghosts" (tablets) via colostomy or in the stool, and that
this is of no concern since the active medication has already been absorbed.

10. Patients should be advised that if they have been receiving treatment with OxyContin� for more than a few weeks and
cessation of therapy is indicated, it may be appropriate to taper the OxyContin� dose, rather than abruptly discontinue
it, due to the risk of precipitating withdrawal symptoms. Their physician can provide a dose schedule to accomplish a
gradual discontinuation of the medication.

11. Patients should be instructed to keep OxyContin� in a secure place out of the reach of children. When OxyContin� is
no longer needed, the unused tablets should be destroyed by flushing down the toilet.

Gli esseri umani e altri mammiferi